The NMN component



了解NMN

目次

NMN是什么成分?

NMN是尼古丁酰胺单核苷酸的简称,是以维生素B3等为材料在体内自然生成的物质,是身体中细胞活动不可缺少的物质。身体中的细胞活动不可缺少的辅酶NAD(烟酰胺腺苷)的前体,存在于所有生物的细胞中。本来NMN是以维生素B3等为材料在体内自然生成的物质,但随着年龄的增长,在体内的生成能力也会减少。

富含NMN的食材是?
西兰花和毛豆中含有多少

NMN含有毛豆、花椰菜、鳄梨等蔬菜、水果、种子类等。即使吃100g,含量也只有2mg左右,在抗老化作用方面量很少,但在体内,例如红细胞中总量估计有50mg左右,所以如果继续吃的话,体内会有相应量的NMN供给。”被认为会被做。
话虽如此,随着年龄的增长生成能力减少的NMN,仅仅从食物中摄取是非常不够的。为了摄取150mg NMN毛豆需要吃约12000个,西兰花需要吃约2400个。另外,如果是鳄梨和西红柿的话大约要摄取600个,如果是虾的话必须摄取10000尾,非常不现实。
因此,通过营养补充剂等从外部补给NMN是很重要的。

食品 相当于NMN300mg
必要的摄取量
毛豆 24000个
西兰花 4800间房
洋白菜 28个
牛油果 720个
番茄 720个
蘑菇 2,400个
牛肉(生的状态) 2,400g
虾仁 12000条

光学异构体
(α-NMN和β-NMN)

NMN具有不同的分子结构α-NMN和β-有NMN两种。α-NMN和β-NMN与构成分子的部件(原子)的种类和数量相同,但其部件(原子)之间的连接方向不同,称为光学异构体。
Α-NMN、β-NMN分子结构的差异示意图。

分子结构示意图
重叠示意图

本来,我们需要的NMNβ-NMN。Β-NMN是由人体生成的,但不必要的α-不会生成NMN。
但是,为了削减成本,通过简单的化学合成制造的NMN,有很高的概率α-NMN和β-NMN混在一起。
Α-完全无NMN混合β-NMN只通过极其精密的制造工序制造。
未来实验室的NMN补充β-是只配合NMN的高品质的产品。

关于NMN中含有的杂质

市面上制造的NMN中几乎都是各种杂质混合在一起的。其中也有不被认为是生物体内物质的物质。一般社团法人产品开发研究机构(IRPA)进行了分析处理NMN的4家公司的NMN原料中含有的杂质是怎样的物质的试验。
首先用LC-UV法(※1)进行分析,用质谱法(MS)对此时可检测出杂质的分离峰进行试验,通过鉴定杂质成分的方法进行调查,结果,在未来实验室的NMN原料中,仅检测出少量含有的杂质“烟酰胺”。

NMN中含有杂质

NMN Sample 本公司NMN SA公司(美国制造商) OK公司(国内N家) Self-Afflmed GRAS认证
(※2)的公司
NMN PURITY(%) 99.0 97.2 98.3 97.5
杂质1
「生物体内物质」
C6H7N2O
「烟酰胺」(※1)
C6H7N2O
「烟酰胺」(※1)
C6H7N2O
「烟酰胺」(※1)
C6H7N2O
「烟酰胺」(※1)
杂质2 C11H25NO9P C11H25NO9P
杂质3 C10H16N5O10P2
杂质4 C9H15N3O8P
杂质5 C9H15N3O7P
杂质6 C9H16N4O8P
杂质7 C10H15N5O2P
杂质8 C21H27N6O15P2

“一般社团法人产品开发研究机构”(IRPA)调查
※1:C6H7N2O“烟酰胺”是生物体内物质,与烟酸一起作为被称为烟酸的营养素,是人可以摄取的物质,是安全的。
※2:Self-Affirmed GRAS认定是指美国的“GRAS”制度(一般认为安全的成分)中
客观评价“GRAS”这一美国国内毒性专家的安全性,得到美国食品药品管理局(FDA)的批准
有Self-Affirmed GRAS(自认证)两种,Self-Affirmed GRAS不是FDA的认可制度。

4家公司所有NMN中含有杂质的”烟酰胺“是生物体内物质,与烟酸一起作为被称为烟酸的营养素,是人可以摄取的物质,是安全的。另一方面,在”OK公司“和”Self-Affirmed GRAS认定的公司“的NMN中,作为杂质”烟酰胺“除此之外还含有多种物质。
特别是,“Self-Affirmed GRAS认证公司”的NMN中除了“烟酰胺”以外还含有6种杂质,这些杂质的安全性没有得到保证,长期摄取含有如此多杂质的NMN的产品时,担心会不会对身体造成影响。
即使标记为配合了高纯度的NMN,实际上也含有怎样的杂质,另外纯度低安全性也没有被确认的NMN配合产品也有销售,请注意。
※1LC-UV(高速液相色谱-紫外线吸收光谱法)

对于真正志向的你,NMN的权威
唯一被认可的未来实验室的NMN补充

NMN的权威今井真一郎华盛顿大学教授警告说:“现在市面上销售的NMN胶囊质量良莠不齐传达着。”唯一出售的产品,其对人体的安全性已被证实,是MiraiLab生物科学公司的产品。本公司杂质极少β-只配合了NMN的营养补充剂及化妆品销售着,那个纯度绝对纯度与99%以上的其他人相比确保着压倒性的高度。另外,在世界上首次进行人体临床研究,因为拥有日本唯一的NMN专业的本公司研究所,所以被评价为担负研究到销售的NMN生物风险企业的先锋。
对真正志向的你,学院品质的未来实验室的NMN sapuri。

可折叠内容

ISN'T THE PRODUCT OF OTHER COMPANIES MORE THAN 99% PURE?

According to various research institutes, the purity of our NMN is 99% or higher, and it has also been confirmed that it is highly safe for both humans and rodents. Only one other company in the world is offering such high-purity NMN nutraceuticals (as of April 2022).

For more information, please see Strong points of Mirai Lab's supplements.

What are the risks related to optical isomers?

For your safety and peace of mind, Mirai Lab's products do not contain any α-NMN at all. Our NMN is manufactured accoding to a special, precise method so that the result is exclusively full β-NMN.
For more information,please see Mirai Lab's NMN substance

What's the β-NMN that you use?

There are two types of NMN, α-NMN and β-NMN, which have different molecular structures.

The molecules α-NMN and β-NMN are called optical isomers because they have the same type and number of atoms, but the connections beetween them point at different directions.
The NMN we need by nature is β-NMN.
β-NMN is produced by the human body, while unnecessary α-NMN is not.
Many companies manufacture NMN following a cheap process of chemical synthesis with the only goal of reducing costs. When they do that, the possibility of ending up with a mixture of α-NMN and β-NMN is very high. Please note that β-NMN, without a trace of α-NMN, can only be produced through a very precise manufacturing process.
Mirai Lab's NMN supplement is a high quality product containing only β-NMN.
For more information, please see Mirai Lab's NMN substance.

Do you conduct human medical studies?

Mirai Lab's NMN was the first in the world to be used in a safety test on humans. In addition to demonstrating its safety, we confirmed the expression of the sirtuin genes, an increase in melatonin and other growth hormones in a long-term (24-week) administration clinical study at Hiroshima University School of Medicine.

Should I take any precautions when using your products?

Please refer to list of ingredients of the products and do not consume if you are allergic to any of them. In rare cases, the products may not suit you depending on your physical conditions.
In that case, please stop the intake. If you are taking any medicine or receiving any medical service, please consult with your doctor before taking. Please observe the recommended daily intake, as a larger dose will not cure any illness or improve your health. Keep out of reach of children.

How much should I take per day?

Please observe the recommended daily intake. Take your supplements with water.

Do your products contain allergens?

Our products do not contain any allergens that must be stated according to the laws of Japan. However, we kindly ask you to read the list of ingredients before you take any of our products. In you find any ingredient that could pose any danger to your health, please do not consume.

Do you use any genetically modified materials in your products?

No, we don't.

I'm breast-feeding. Can I take your products?

Since this product is not a drug, it can be taken just like any other food.

However, you can find the list of ingredients and warnings on the product details page and package, so if you have any allergies or other concerns, please read them and consult your physician before consuming.

Is there a Best-before or a Use-by date?

Yes, there is.
Generally speaking, you can consume your products within 2 years after manufacture, but you have more details on the product package.
Please do not hesitate to contact us viaWeb inquiryon if you need further information.

How should I store your products?

Please keep them in a cool, dry place away from direct sunlight.

Are there any side effects?

We haven't received any reports regarding side effects, but before using the products, please refer to the list of ingredients if you have any allergies.